E
- E. Jean Carroll Notable People
- E. Jean Carroll: raised on Illsley Place Famous People
- E. Ross Adair Notable People
- EACS Early Childhood Preschool Schools & Colleges
- The Early Parks, One by One — Swinney to Hamilton, 1869–1908 Parks & City Planning
- East Allen Career Center Schools & Colleges
- East Allen University Schools & Colleges
- East Central Neighborhoods
- East State Boulevard — the trolley corridor Main Roads & Corridors
- East State Village Neighborhoods
- The Eastern Star in brief Lodges & Fraternal Orders
- Easterseals Northeast Indiana Charities
- The Economy Motor Buggy Company: Fort Wayne's motor-buggy factory Automobiles
- Ed Viesturs — born here, raised in Rockford, first American up all fourteen Notable People
- Edith Hamilton Notable People
- Edith Hamilton — the classicist of Clinton and Lewis Authors & Books
- Edith Hamilton: the classicist Fort Wayne raised Famous People
- Edward A. and Joan White — Bowmar's founding household Founders & CEOs
- Edward A. K. Hackett Notable People
- Edward F. Perrey, the city's commercial eye Photographers
- Edward G. Hoffman Notable People
- Edward O'Rourke Notable People
- Eel River Elementary School Schools & Colleges
- The Eel River: the western approach The Three Rivers
- The electric pig: a claim that fails, and the Fort Wayne part that stands Inventors & Inventions
- Electric Works — the General Electric Broadway Campus Famous Landmarks
- Electric Works: the deal the city killed and then revived City Controversies
- The electrical cluster · from arc light to General Electric Industrial Revolution
- "Elevate the Nickel Plate" — the north side waits forty years, 1947–1956 Railroads
- Elevating the south side — the Pennsylvania and Wabash go up, 1909–1914 Railroads
- Eleven days of Mayor Simon Strange but True
- Eliza George Notable People
- Elks, Eagles and Moose: the convivial layer Lodges & Fraternal Orders
- Elmhurst High School Schools & Colleges
- The Embassy as a stage: vaudeville, the rescue, and the Broadway tours Arts
- The Embassy Theatre and Indiana Hotel (1928) — the Movie Palace the City Saved Architecture
- The Embassy Theatre and the Ghost of Bud Berger Ghost Stories
- The Embassy Theatre's ghost is stage manager Bud Berger. Famous Stories & the Record
- Emboyd Theatre (Embassy Theatre) and the Indiana Hotel Businesses
- The Emerine J. Hamilton Free Reading Room for Women Libraries
- Emmanuel Lutheran Church (1867) Churches & Religion
- Emmaus Lutheran Church (1900) Churches & Religion
- The Empress, the Strand, and the Shirley: the Wayne Street corner house Theaters
- The enablers · canal, wire and rail Industrial Revolution
- Engineer John: children's television comedy on WKJG Comedy
- The English Fortune: Lincoln Life Stock and the English-Bonter-Mitchell Foundation Great Fortunes
- The English-Bonter-Mitchell founding gift: three friends endow a physician's memory Major Donations
- English-Bonter-Mitchell: the Fort Wayne fortune administered from Pittsburgh Foundations & Nonprofits
- Epidemics & Public Health Section
- The eras of growth, read off the numbers Population
- Erastus B. Kunkle Notable People
- Eric Wedge: Northrop's state champion who managed a pennant race Sports Players
- Ernst C. Rurode Notable People
- ESACS Virtual School Schools & Colleges
- The Escapes, at the Size the Record Gives Them Zoo
- Essex Wire Corporation — Fort Wayne Plant Notable People
- Essex Wire Corporation — Fort Wayne plant (later Essex Group / Essex International / Superior Essex) Businesses
- Ethan Sandler: the writer-producer's ladder Film & TV Producers
- Ethos — progressive rock band Notable People
- Eugene E. Parker — the Fort Wayne agent who ran football from here Notable People
- Eugenics: the first law in the nation, and Fort Wayne at its center Mental Health Institutions
- Events Calendar Section
- The Ewings: William G. and George W. Ewing Great Fortunes
- Exclusion and decline · what Article XIII did here Black History
- Exports Section
- The expressway fight · the referendum that saved East Central Black History